The Cleveland Clinic and ASM will offer blended technical programming covering the spectrum of materials-related challenges and opportunities in medicine, from today's materials to the next generation of nanomaterials.
ASM will offer materials and process-related seminars for engineers and physicians who work with medical devices, with CME accreditation. Exhibits will feature advances in materials and processes for medical devices from both manufacturers and suppliers.
Co-Director of the BioMEMS Laboratory at the Cleveland Clinic's Lerner Research Institute, Department of Biomedical Engineering.
With strong traditions of innovation and research, the Cleveland Clinic Foundation is strategically positioned to investigate and develop BioMEMS. Furthermore, the research environment at the Lerner Research Institute is unique as it provides the necessary multidisciplinary collaboration that will be required for the implementation of new and novel ideas into successful BioMEMS.
Associate Professor, Materials & Metallurgical Engineering Department, South Dakota School of Mines and Technology
A leading expert on materials for orthopedic applications who was previously principal engineer for Zimmer Inc., Medlin will describe major trends in minimally invasive surgical (MIS) procedures, which radically reduce the size of the surgical incision and potentially causes less damage to the soft tissue surrounding the replaced joint. Results of MIS include less postoperative pain, shorter hospital stays, faster recovery times and an overall lower cost to the health care system.
Professor of Electrical and Computer Engineering, Purdue University, Birck Nanotechnology Center
The idea of miniaturizing the electronic detection of microorganisms into a biochip has resulted in a start-up (BioVitesse, Inc.) that Bashir co-founded in May 2002. Employing the specificity of biological interactions and the rapidity of electronic detection in a micro-mechanical biosensor is part of the broader research in bioMEMS and bionanotechnology that takes place in Bashir's highly multidisciplinary lab at Purdue University. His group is engaged in solving problems at the interface of micro and nano-engineering and the life sciences.
Assistant Professor, Case Western Reserve University
Dr. Baskin is an Assistant Professor at CWRU and a University Hospitals Health System (UHHS) physician. He is board certified in Otolaryngology-Head & Neck Surgery as well as Facial Plastic & Reconstructive Surgery.
Chairman of the Cleveland Clinic Spine Institute, the Director of the Neurological Surgery Residency Program, the Director of the Spine Surgery Fellowship Program, and Vice-Chairman of the Department of Neurological Surgery at Cleveland Clinic.
Dr. Benzel will discuss the future of spine surgery and opportunities for using Micro-Electro-Mechanical Systems (MEMS) and nanotechnology which will allow neurosurgeons to perform tasks with greater precision, perform tasks that previously were not done at all, and monitor patients more accurately and with greater safety.
Project Staff, Department of Biomedical Engineering, Cleveland Clinic Lerner Research Institute.
Calabro’s general research interests include the structure, function and metabolism of Hyaluronan and Aggrecan in normal, malignant and arthritic tissues.
Co-Founder and Managing Director, Granta Design Limited.
Cebon has 15 years experience at the cutting edge of materials and process selection methodology and software. He is the architect of all generations of Granta Design's products, which help enterprises manage, analyze, and apply critical data in the engineering process. He holds positions as Reader of Engineering at Cambridge University and Fellow of Queens' College, Cambridge. He has a Ph.D. in Engineering from Cambridge University and a Bachelor’s Degree from Melbourne University, Australia.
Professor of Pediatrics, Medicine, Physiology & Biophysics, and Molecular Biology & Microbiology Case Western Reserve University, Department of Biochemistry.
The goal of Dr. Davis‘ research is to understand the pathophysiology of the genetic disease cystic fibrosis and to devise means to ameliorate or cure it. To this end, she studies the structure and function of the protein defective in this disease, CFTR, the sequence of events leading from defects in this protein to the lung infection and excessive inflammation that ultimately takes the patients, lives and strategies for genetic correction of the disease. Her research areas focus on regulation of gene expression, metabolic regulation and gene therapy.
Professor of Physiology and Director, Laboratory of Therapeutic Micro and Nanotechnology, University of California, San Francisco
The Desai lab is designing templates to achieve cardiomyocyte attachment and orientation in dynamic environments, nanoporous metal-oxide films for osseointegration, and have applied microfluidic biopolymer patterning to design multicellular and multilayered vascular analogues. The potential of using such techniques to recreate hierarchical tissue architecture makes this an exciting tool for cellular and tissue engineering.
Research Associate Professor of Materials Science and Director of the Advanced Polymers Laboratory, University of New Hampshire
Durant earned a degree in chemistry and chemical engineering in from Ecole Nationale Supérieure de Chemie de Montpellier, received his Ph.D. in polymer chemistry from the Université Claude Bernard, Lyon I in France and an MBA from the University of New Hampshire. He has worked as both scientist and project leader in the Polymer Laboratory within BASF AG, Germany and has been an active industrial consultant. Durant’s areas of research interests include polymer dispersions, drug delivery, nanostructured polymers, and polymerization kinetics.
Exponent Failure Analysis Associates
Eiselstein is Principal Engineer in Exponent's Materials/Metallurgy practice. He specializes in the mechanical behavior of materials, corrosion science, engineering and testing. His research includes design, analysis and testing for FDA approval of implantable devices, electrochemical/mechanical measurements, fatigue, design and fabrication of metal laminates for reactive armor, development of lightweight armor, and ballistic testing.
Assistant Staff Member, Cleveland Clinic Lerner Research Institute
An assistant staff member in the Department of Biomedical Engineering, Fleischman’s research focuses on the development of BioMEMS, particularly microfabricated diaphragms for fiber optic pressure sensors and the use of silicon carbide as a biocompatible material.
Assistant Professor, Department of Internal Medicine, University of Michigan.
A specialist in Nephrology, Dr. Fissell’s research interests include tissue engineering and nanofabrication. He received his M.D. from Case Western Reserve University (1998) and was a resident at University Hospitals of Cleveland.
Assistant Professor, Bioengineering University of California, Berkeley
Fletcher is interested in the use of atomic force microscopy, near-field microscopy and MEMS-based sensors for investigating mechanical properties and transport properties of cells and tissues. The Fletcher Lab studies the mechanics and dynamics of cell motility and shape change on three levels: purified proteins, whole cells and groups of cells. Based on their understanding of cell and molecular mechanics, the lab is developing medical devices that aid in clinical diagnosis and treatment of disease.
Co-Director, Surgical Innovation Program, Stanford University School of Medicine
Dr. Gertner was trained in mechanical engineering at Columbia and MIT, then in Medicine at Cornell Medical College. He trained in General Surgery at UCSF where, during his residency, he became interested in the power of nanotechnology to address unmet clinical needs. He founded Nanomedical Technologies and advanced a novel drug coating process through proof of concept, after which it was acquired and is now in the pre-clinical testing stages. For this effort, he was named one of the top 100 Innovators under 35 by Technology Review Magazine. His current efforts are focused on teaching the process of innovation to surgeons at Stanford and furthering nanotechnology-based medical science.
Corporate Scientist (Retired), 3M Biosciences Laboratory
A Founding Fellow of the American Institute of Medical and Biological Engineering and a consultant to the Whitaker Foundation, Gibbons was a staff scientist and corporate scientist at 3M Biosciences Laboratory from 1982 until his retirement in 2003. From 1968-1973, he was Professor of Biomedical Engineering and Director of the Center for the Study of Materials at Case Western Reserve University, and from 1974-1981 he was Professor of Biomedical Engineering (School of Engineering), Professor of Experimental Pathology (Medical School) and Adjunct Staff Member for the Department of Artificial Organs at the Cleveland Clinic.
Director of the Innovative Ventricular Assist System (IVAS) Program at Cleveland Clinic
Dr. Golding will discuss the state-of-the-art cardiac pump for use in patients with terminal heart failure that was developed at Cleveland Clinic. The pump is designed to replace the function of the left ventricle muscle - either partially or completely - in these patients. The pump is part of the CorAide Cardiac Assist System which is currently in clinical trials in the United States and already being used by some patients in Europe.
Cleveland Clinic
Dr. Greenberg specializes in vascular, thoracic and cardiovascular surgery, and also works in biomedical engineering. His interests include carotid artery surgery, thoraco-abdominal aortic repair/reconstruction, thoracic aortic aneurysm repair, abdominal aortic aneurysm repair, peripheral artery/vein repair/bypass surgery, aortic aneurysm stent repair, endovascular stent repair, and endovascular stent research.
Assistant Professor, The Ohio State University, Chief Scientist, Microfabrication, Ohio MicroMD Laboratory
The recipient of a TR100 award from MIT's Technology Review, Hansford is a joint faculty member with Biomedical Engineering and the Biophysics graduate program at Ohio State. His research interests range from theoretical biofluid flow modeling through nanochannels to novel microfabrication protocol development for biomedical microdevices and conducting polymer circuitry. Recent research has focused on the microfabrication of polymers to produce microdevice drug delivery systems and nanochannels for the controlled motion of biomolecules in solution.
Co-Director, Orthopaedic Research Center, Department of Biomedical Engineering, Cleveland Clinic, Lerner Research Institute
Hascall’s area of general research interest is Connective Tissue Biology. His current program is Structure, Function and Metabolism of Proteoglycans and Hyaluronan in Connective Tissues. Proteoglycans are specialized proteins containing one or more covalently bound glycosaminoglycan chains: chondroitin/dermatan sulfate, keratan sulfate, heparin/heparan sulfate, or a combination of types.
Senior Vice President, BioPharma, Advance Nanotech.
Before joining Advance Nanotech, Helmus served as the Vice President, Advanced Biomaterials at Boston Scientific. Prior to that Dr. Helmus held research and development positions with organizations including Edwards Lifesciences, Baxter CVS, Pfizer, and Arthur D. Little. His expertise includes the identification and acquisition of new technologies, implementation and management of research and development programs, and intellectual property development and management.
President, Nitinol Technology, Inc.
Hodgson is a recognized authority on properties, fabrication and device issues regarding Nitinol alloys. In 1987, to provide Nitinol forms and custom shapes to primarily medical customers, he founded Shape Memory Applications which was later sold to Johnson Matthey, Inc. Nitinol Technology, Inc., was founded in 2001 as a small product development and consulting firm. Hodgson is a founding member of the International Organization on Shape Memory and Superelastic Technologies (SMST) and served as Secretariat of the first SMST Conference in 1994 and as Chairman of SMST ’97. He is Chairman of the ASM Strategic Planning Committee involved with meeting the materials needs of the medical community.
Principal Engineer, Exponent Failure Analysis Associates
James specializes in failure analysis, metallurgy, fracture, fatigue, corrosion and material degradation issues. He has conducted hundreds of medical device failure analysis investigations for both industrial and legal clients. He also helps medical device companies with general materials and/or metallurgical issues, as well as pre-market validation for fatigue, fracture and corrosion performance.
Vice President, BioEnterprise
BioEnterprise is a business formation, recruitment and acceleration initiative designed to grow health care companies and commercialize bioscience technologies. Lang leads the company’s efforts for advising and evaluating medical device and equipment companies. He has played key roles in the initiation of five new organizations including new divisions of Johnson & Johnson and Avery Dennison. He has extensive experience in products as varied as implants, biomaterials, specialty instrumentation, minimally invasive surgical therapies, and biomaterials for wound healing applications. He also has extensive product launch experience in the orthopedic, cardiovascular, neurological and general surgery markets.
Polymer Chemist (Retired), TechCon
From 1965 until his retirement in 2003, Lange worked with The Lubrizol Corporation, a fluid technology company. As a Principal Research Scientist from 1997 through 2003, he was a member of the corporate Technical Ladder, comprising a select group of senior technologies within the Research Division. His areas of expertise include polymers for both aqueous and non-aqueous media, development of new polymers and polymer additives, and development of polymeric dispersants.
Professor, University of Alabama at Birmingham
Dr. Lemons' research has focused on the biocompatibility profiles of surgical implant devices with an emphasis on the roles of element and/or force transfers along biomaterial-to-tissue interfaces. Current projects include characterization of cell/fluid interactions with titanium and zirconium alloy surfaces; in vivo and in vitro bone responses to surface modifications of titanium alloy implants; biomechanical properties of implant stabilized removable dentures; in vivo explant and in vitro analyses of polyglass crown and bridge restorations; in vivo and in vitro evaluation of metallic-metallic and metallic-polymeric wear of total joints; and biocompatibility aspects of nanocrystalline carbon and hydroxyapatite modifications of alloys for temporomandibular joint replacement.
Cleveland Clinic, Lerner Research Institute
Dr. Muschler is a member of the staff in Orthopaedic Surgery, the Transplantation Center, the Department of Biomedical Engineering and the Cancer Center Division Office. His specialty interests include arthritis surgery, joint replacement of the hip and knee, and treatment of fracture non-union.
Assistant Professor, Department of Physics, Georgetown University
Most of his research activity is conducted at the Georgetown Advanced Electronics Laboratory (GAEL). GAEL's specialization is in Health Microsystems, and its mission is to improve health care and quality of life through the design, fabrication and testing of integrated micro-monitoring systems and drug delivery micro-systems, using state-of-the-art physical science, pharmacology, and bio-engineering technologies.
Nitinol Devices and Components, a J&J Company
In 1993, Pelton joined Nitinol Devices and Components, where he is a Senior Research Fellow and Director of Research and Process Development. His current interests include corrosion and fatigue of Nitinol medical devices. He has 80 publications in the field of shape memory alloys, and co-edited Images of Materials and the Proceedings of SMST-94, SMST-97, SMST-2000, and SMST-2003. He co-founded SMST (Shape Memory and Superelastic Technologies) in 1993.
Cleveland Clinic
Dr. Rasmussen is a member of the staff in Neurological Surgery, Gamma Knife Center and Diagnostic Radiology. His specialty interests include endovascular and microsurgical management of cerebral aneurysms, AVMs, fistulas, spinal cord vascular malformations, carotid endarterectomy, carotid and intracranial angioplasty and stenting.
Chairman of the Center for Neurological Restoration and Director of the Brain Neuromodulation Center at Cleveland Clinic.
Dr. Rezai is one of the leading functional neurosurgeons in the world and was among the first in the country to perform a highly promising neurosurgery procedure involving the use of a "pacemaker" for the brain that halts the occurrence of tremors in patients with Parkinson’s disease. At the Summit, Dr, Rezai will discuss the brain surgery technique called deep brain stimulation and ways the pacemaker device has led to improved quality of life from patients suffering with Parkinson's disease, migraine headaches or other chronic pain syndromes, depression, obsessive-compulsive disorders, and stroke survivors.
Founder and President, MicroCHIPS
Honored by Technology Review Magazine as one of the Top 100 Young Innovators in the world, Santini is a member of the Governing Council of the MEMS Industry Group, a national trade organization dedicated to the advancement and commercialization of MEMS technology in the United States. MicroCHIPS is best known for developing an implantable computer-controlled device that can release drugs into the body as programmed. The technology will also be used to activate biosensors in the body and for the passive delivery of drugs in orthopedic implants like hips or knees.
R&D Manager,Endovascular Technologies, Abbott Vascular
Shrivastava was named one of the 100 most notable people in the medical device industry by Medical Device & Diagnostic Industry magazine and has been instrumental in developing materials for implantable medical devices. He will describe the impact of materials on the development of minimally invasive procedures and implants, which have replaced many complex surgical procedures during the past decade. Currently developing novel stent materials at Abbott Vascular Devices in Redwood City, California, Shrivastava also worked for Edwards Lifesciences on novel processes and materials for heart valves and peripheral stent applications. He served as the chairman of ASM's first-ever Materials and Processes for Medical Devices Conference and has written two books on medical device materials and the heat treating of materials.
Cleveland Clinic
Dr. Toms is director of Metastatic Diseases within The Cleveland Clinic Brain Tumor Institute and a member of the staff for Neurological Surgery, Spine Institute, Cancer Biology, and Cancer Center Division Office. His specialty is complex brain and spinal tumors in adults and children.
Principal Engineer, Neuro-Modulation R&D Codman and Shurtleff, A J&J Company.
From 1998-2002, Venugopalan was an Assistant Professor in BME at the University of Alabama-Birmingham with a research focus on mechanical-electrochemical interactions in medical devices and its impact on device design and lifetime. He transitioned to the role of a Principal Engineer in Neuro-Modulation R&D for Codman and Shurtleff, A J&J Company (Raynham, Mass.) in 2002, while continuing to maintain an adjunct faculty position at BME/UAB. He also serves on the JBMR: Applied Biomaterials Editorial Board and is a reviewer for the NIH-SBIR/STTR (ZRG1-SSS-5) study section.
Assistant Professor, Case Western Reserve University, Biomedical Engineering.
Von Recum's research focuses on building artificial blood vessels with small diameter (~4-6mm in diameter). Small-diameter blood vessels are extensively used in heart bypass surgeries and similar biomedical procedures. Unfortunately, the human body has a limited supply of "extra" blood vessels that can be transplanted to the surgical area. Also, current small-diameter synthetic vessels have problems with compatibility and uncontrolled blood clotting. Von Recum's new artificial blood vessels address a critical unmet biomedical need. He is also investigating the use of stem cells for new tissue engineering therapies.
Associate Professor, Division of Engineering, Brown University and Division of Orthopedic Surgery at Brown University Medical School
Webster’s research addresses the design, synthesis and evaluation of nanophase materials as more effective biomedical implants. He is the current director of the Nanostructured Biomaterials Laboratory and has completed extensive studies on the use of nanophase materials as implanted materials. A team of engineers led by Webster showed that zinc or titanium oxide nanosurfaces can reduce the presence of bacteria, a technique that can be applied to implants to reduce the number of these costly and debilitating infections.
Professor of Medicine, Physics, Biomedical Engineering, and Cell Biology and Physiology, Cardiovascular Magnetic Resonance Laboratories, Cardiovascular Division, Barnes-Jewish Hospital at Washington University Medical Center
The National Cancer Institute (NCI) has awarded $16 million over five years to the Washington University School of Medicine to establish the Siteman Center of Cancer Nanotechnology Excellence (SCCNE). Headed by Dr. Wickline, the SCCNE will research and apply nanotechnology for the diagnosis and treatment of cancer. Dr. Wickline and Gregory M. Lanza, M.D. have developed nano-scale particles that can home in on tumor cells to carry imaging agents and drug therapies directly to tumor sites.
Associate Staff, Department of Biomedical Engineering, Cleveland Clinic Lerner Research Institute.
Zborowski's areas of general research interest include separation processes for medical applications. His current research involves continuous magnetic cell sorting, cell tracking velocimetry, magnetic nanoparticle characterization, and magnetic and fluid dynamics in cell separation.
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