{"id":8296,"date":"2014-05-20T15:33:57","date_gmt":"2014-05-20T15:33:57","guid":{"rendered":"https:\/\/staging.asminternational.org\/hts3-new\/results\/-\/journal_content\/56\/10192\/19004334\/NEWS\/"},"modified":"2023-02-07T04:48:20","modified_gmt":"2023-02-07T04:48:20","slug":"implant-coating-promotes-bone-growth","status":"publish","type":"post","link":"https:\/\/www.asminternational.org\/ims-new\/results\/-\/journal_content\/56\/10192\/19004334\/NEWS\/","title":{"rendered":"Implant coating promotes bone growth"},"content":{"rendered":"<p>\n\tResearchers at Uppsala University, Sweden, developed a responsive coating for implants to improve their integration into bone and to prevent rejection. Neutron scattering experiments at the Institut Laue-Langevin (ILL), France, show how a protein that promotes bone growth binds to this surface and can be released in a controlled way. Gels made by modifying hyaluronan, a biological molecule, can coat implants. Research shows the coated titanium surfaces can bind protein molecules that promote bone formation.<\/p>\n<p>\n\tThese can be released slowly once the surface comes in contact with a solution of calcium ions. This process stimulates bone growth on implants. The gel layers, a few millionths of a millimeter thick, were characterized using neutron reflection at ILL, providing a detailed surface image. BMP-2, the protein that encourages bone growth, was bound to the gel. The protein layer was stable in water, but could be released slowly by adding solutions containing calcium, a process that was observed in real time using neutron reflection to track the amount of protein at the surface. <em><a href=\"http:\/\/www.uu.se\/en\">www.uu.se\/en<\/a>.<\/em><\/p>\n<p>\n\tImage caption &#8211; A gel-coated titanium surface binds proteins that promote bone formation. Courtesy of Ida Berts.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at Uppsala University, Sweden, developed a responsive coating for implants to improve their integration into bone and to prevent rejection.<\/p>\n","protected":false},"author":63082,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-8296","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Implant coating promotes bone growth - International Metallographic Society - New<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Implant coating promotes bone growth - 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