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Professor Kaushik Chatterjee Special Seminar

  • April 19, 2018
  • Roberts Hall
  • Seattle , WA , USA

Description

Nanoscale Engineering of Materials for Orthopedic Applications

 

Kaushik Chatterjee

Department of Materials Engineering & Centre for Biosystems Science and Engineering, Indian Institute of Science, Bangalore

 

Bone disorders resulting from disease and trauma are a major healthcare burden worldwide. This has motivated the development of biomaterials for replacement and regeneration of the bone tissue. In our group, we work on engineering materials for use in biomedical devices and as scaffolds for bone tissue regeneration encompassing a variety of materials including metals, polymers and composites. Our group has developed several nanoscale strategies to enhance the mechanical performance and biological response to materials.

Two different nanoscale surface engineering techniques are being developed to improve the performance of titanium and its alloys for use in orthopedic devices. In one strategy, we have developed nanoscale pillars inspired by insect wings that are bactericidal and yet compatible with human stem cells. In another approach, we induce surface nanocrystallization through severe surface deformation that enhances the fatigue properties and the cellular response to these materials.

Toward preparing scaffolds for bone tissue engineering, we are exploring the use of nanoparticle for improving the bioactivity of polymers. We have demonstrated that graphene can fuctionalized to impart a combination of osteogenic, angiogenic and bactericidal activity to the polymer composite. In a different approach, we have prepared nanocomposite polymer fibers incorporating ceramic nanoparticles that elute bioactive ions.

Taken together, we have developed several strategies to impart multifunctional properties to materials for use in orthopedic applications.

 

Speaker’s background: Dr. Kaushik Chatterjee received his Ph.D. from Penn State University and was a postdoctoral fellow working jointly at the National Institute of Standards and Technology and the National Institutes of Health. He joined the Indian Institute of Science, Bangalore in 2011 where he is currently an Associate Professor in the Department of Materials Engineering and is associated with the Centre for Biosystems Science and Engineering.

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